BDNF mRNA abundance regulated by antidromic action potentials and AP-LTD in hippocampus

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BDNF mRNA abundance regulated by antidromic action potentials and AP-LTD in hippocampus

Action-potential-induced LTD (AP-LTD) is a form of synaptic plasticity that reduces synaptic strength in CA1 hippocampal neurons firing antidromically during sharp-wave ripples. This firing occurs during slow-wave sleep and quiet moments of wakefulness, which are periods of offline replay of neural sequences learned during encoding sensory information. Here we report that rapid and persistent d...

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ژورنال

عنوان ژورنال: Neuroscience Letters

سال: 2016

ISSN: 0304-3940

DOI: 10.1016/j.neulet.2016.10.023